Social constraints, genetic vulnerability, and mental health following collective stress

A repeat-length polymorphism of the serotonin promoter gene (5-HTTLPR) has been associated with depression and posttraumatic stress disorder (PTSD) in trauma-exposed individuals reporting unsupportive social environments. We examine the contributions of the triallelic 5-HTTLPR genotype and social constraints to posttraumatic stress (PTS) symptoms in a national sample following the September 11, 2001 (9/11) terrorist attacks. Saliva was collected by mail from 711 respondents (European American subsample n = 463) of a large national probability sample of 2,729 adults.

FKBP5 and CRHR1 polymorphisms moderate the effects of child abuse and adult stress on physical health

OBJECTIVE: Stressful life events experienced during childhood and as an adult negatively impact mental and physical health over the life span. This study examined polymorphisms from 2 hypothalamic-pituitary-adrenal axis-related genes previously associated with posttraumatic stress disorder-FKBP5 and CRHR1-as moderators of the impact of child abuse and adult stress on physical health.

Psychological Distress and Susceptibility to Cardiovascular Disease Across the Lifespan: Implications for Future Research and Clinical Practice

Stress and psychological distress are known powerful, modifiable risk factors for cardiovascular disease (CVD) 12345 , yet we know little about when or how the processes underlying this relationship begin. Indeed, prospective lifespan research that connects childhood experience with subsequent CVD-related outcomes to inform development of appropriate early interventions has been lacking.

Feasibility of a Mindfulness-Based Stress Reduction Program for Early-Stage Breast Cancer Survivors

Purpose: To assess the feasibility of whether mindfulness-based stress reduction (MBSR) has a positive effect on breast cancer survivors’ psychological status, psychosocial characteristics, symptoms, and quality of life (QOL) during the critical transition period from end of treatment to resumption of daily activities.

Psychosocial stress and social support as mediators of relationships between income, length of residence and depressive symptoms among African American women on Detroit's eastside

 Patterns of mental health are clearly associated with life circumstances, including educational and economic opportunities, access to safe and supportive neighborhoods, socially structured exposures to stressors and to supportive relationships. In this article, we examine the social and economic correlates of depressive symptoms among African American women residing within a predominantly African American urban neighborhood in Detroit, USA, with relatively few economic resources.

Stress and Coping of Midlife Women in Divorce Transition

This article describes stress and coping by decider status. Participants were 154 women aged 34 to 54 years who were recently divorced from their first marriage and were married 3 years prior to divorce. Participants self-selected into decider statuses as initiators, noninitiators, or mutual deciders. Noninitiators indicated not knowing the divorce experience was going to occur, not having enough time to get ready for it, saw it as something someone else did, and perceived it as a threat. Initiators and mutual deciders viewed the divorce as a challenge.

Urban Hypertensive African American Grandparents: Stress, Health, and Implications of Child Care

Because stress is a major factor in hypertension, research on parenting stressors and lifestyle behaviors of grandparents with hypertension is important. This study describes urban African Americans caring for grandchildren and examines effects of perceived parenting stressors on hypertension self-management. Hypertensive African American grandparents (N = 49) residing in a large Midwestern city participated in the study. Structured interviews collected descriptive data and the Index of Parental Attitudes (IPA).

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